MOTS-C

Description

Also known as: Mitochondrial Open Reading Frame of the 12S rRNA-c

CAS Number: 1480743-81-5
Molecular Formula: C₆₂H₉₈N₁₈O₁₄
Molecular Weight: ~1394.5 g/mol
Form: Lyophilized Powder
Quantity: 10mg, 40mg
Purity: ≥ 98% (HPLC Verified)

Product Overview

MOTS-c is a naturally occurring mitochondrial-derived peptide (MDP) encoded within the 12S rRNA of mitochondrial DNA. It plays a regulatory role in cellular metabolism and has been the subject of research into insulin sensitization, fatty acid oxidation, and stress resistance pathways, particularly in skeletal muscle and liver models. Studies suggest MOTS-c may:

Improve glucose metabolism and insulin signaling

Activate AMPK and other metabolic regulators

Enhance mitochondrial function under stress conditions

Support weight regulation and metabolic health in preclinical models

Applications in Research

Research on type 2 diabetes and insulin resistance

Investigations into mitochondrial biogenesis and homeostasis

Models exploring aging, metabolic syndrome, and obesity

Studies on cellular resilience to oxidative and nutritional stress

Storage & Handling: Store lyophilized peptide at -20°C, protected from light and moisture. Reconstitute with sterile bacteriostatic water. After reconstitution, store at 2–8°C and use within typical laboratory stability windows. Avoid repeated freeze-thaw cycles.

Research Use Only – Legal Disclaimer

All Eagle Peptides products labeled as Research Use Only (RUO) are intended strictly for laboratory, investigational, and scientific research purposes. These materials are not approved by the FDA and are not intended for human or veterinary use, clinical applications, diagnostic procedures, or therapeutic treatment of any kind. By purchasing or using RUO materials, you acknowledge that they will be handled only within an appropriate research environment by qualified personnel who understand the risks, limitations, and regulatory requirements associated with experimental compounds. Products must not be administered to humans or animals, offered as therapeutic agents, or represented as safe or effective for any medical purpose. Use of these materials is entirely at your own risk. Eagle Peptides assumes no liability for misuse, unsafe handling, improper application, or any regulatory or compliance issues arising from their use.